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@@ -6,9 +6,9 @@ Create a mouse to human brain reference atlas based on homologous gene expressio
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@@ -6,9 +6,9 @@ Create a mouse to human brain reference atlas based on homologous gene expressio
**Description:**
**Description:**
Using information from the Allen Brain Atlas, we want to create a reference map comparing the mouse to the human brain. We want to accomplish this by comparing the mouse ISH data to the human Microarray data and compare the expression of homologous genes.
Using information from the Allen Brain Atlas, we want to create a reference map comparing the mouse to the human brain. We want to accomplish this by comparing the mouse ISH data to the human Microarray data and compare the expression of homologous genes.
**Process (so far):**
## Process (so far):
## Creating the gene subset
**Creating the gene subset**
Got file from Jo with the genes from the AGEA mouse expression map:
Got file from Jo with the genes from the AGEA mouse expression map:
*mouse_gene_list_Jo.csv*, with:
*mouse_gene_list_Jo.csv*, with:
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@@ -18,11 +18,13 @@ Got file from Jo with the genes from the AGEA mouse expression map:
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@@ -18,11 +18,13 @@ Got file from Jo with the genes from the AGEA mouse expression map:
Got files from ensemble site: (http://www.ensembl.org/biomart/martview/9ecad8bf85d46c67fe95b2385e8d2179)
Got files from ensemble site: (http://www.ensembl.org/biomart/martview/9ecad8bf85d46c67fe95b2385e8d2179)
where I took the mouse gene database, filtered for orthologous human gene only and generated two lists (.csv) with unique results only.
where I took the mouse gene database, filtered for orthologous human gene only and generated two lists (.csv) with unique results only.
*Mouse_to_Human_list_withNCBI_ID*, with:
*Mouse_to_Human_list_withNCBI_ID*, with:
- Gene Stable ID
- Gene Stable ID
- Gene Stable ID version
- Gene Stable ID version
- Gene name
- Gene name
- NCBI Entrez ID
- NCBI Entrez ID
*Mouse_to_Human_list_withhumanname*, with:
*Mouse_to_Human_list_withhumanname*, with:
- Gene stable ID
- Gene stable ID
- Gene stable ID version
- Gene stable ID version
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@@ -40,4 +42,5 @@ Using python/pandas I cleaned up and merged these .csv files until I got 1 file
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@@ -40,4 +42,5 @@ Using python/pandas I cleaned up and merged these .csv files until I got 1 file